Tissue Engineering - Simulating organs and tissues

Supervisor : Leila Mostaço-Guidolin

Team size: Minimum 2, Maximum 4

CSE SE Comm Biomed EE Aero Special
YesYesNoYesYesNoNo

Description

**THE PROJECT IS CLOSED. I AM NOT ACCEPTING MORE STUDENTS IN THIS GROUP. THANKS FOR YOUR INTEREST** In tissue engineering, one of the biggest challenges is to be able to simulate the conditions cells find in our bodies. Biochemical and mechanical cues are important elements in organs and tissues, which cause the cells to behave in certain ways (e.g. heal injuries, migrate from one site to another, etc). In this project, students will develop a low-cost stretch chamber able to deform 3D bioprinted tissues and record biomechanical information from the sample (e.g. deformation coefficient) and allow the user to control parameters such as frequency of deformation and intensity. If the group manages to complete a functional prototype, I will provide you with real 3D bioprinted samples to test your device. To see an example of this system, please watch these videos: https://www.youtube.com/watch?v=ByR__cTHQvA https://www.cellscale.com/?_vsrefdom=adwords

Prerequisites:

Hardware, data analysis, strong programming skills

Keywords:

tissue engineering, tissue deformation